Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents
نویسندگان
چکیده
منابع مشابه
Anticancer effects of the metabolic products of the resveratrol analogue, DMU-212: structural requirements for potency.
The methoxylated trans-stilbene resveratrol analogue, (E)-3,4,5,4'-tetramethoxystilbene (1), has shown promising antiproliferative activity in in vitro cell line and in vivo models. In vivo 1 gives rise to several metabolic products through demethylation or hydroxylation reactions at the stilbene moiety. In the present study we examined the anticancer activity of 1 and the metabolites (E)-3'-hy...
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ژورنال
عنوان ژورنال: Bioorganic & Medicinal Chemistry Letters
سال: 2015
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2015.05.019